Inceptive articles Immunohistochemical localisation of d- beta -aspartic acid in pingueculae
Background: d -β -Aspartic acid residues, which are biologically uncommon, carry been reported to accumulate in manifold proteins of the living oppose with age. In the manifest study, d -β -aspartic acid-containing proteins were inaugurate to be localised in pingueculae, which equate one of the most prominent age-related ocular changes. Methods: Surgical specimens of conjunctivae with or without pingueculae were obtained from eight patients. Immunohistochemical localisation of d -β -aspartic acid-containing proteins was performed using a polyclonal antibody against d -β -aspartic acid-containing peptides. Results: Strong immunoreactivity to d -β ...
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